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Melan-A Polyclonal Antibody

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说明书下载
货号: PD4900
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: Melan-A
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 15kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Melan-A Polyclonal Antibody detects endogenous levels of Melan-A protein.
基因名称 : MLANA
蛋白名称 : Melanoma antigen recognized by T-cells 1
别名 : MLANA;MART1;Melanoma antigen recognized by T-cells 1;MART-1;Antigen LB39-AA;Antigen SK29-AA;Protein Melan-A

数据库链接:

Organism

基因 ID

SwissProt

背景:

tissue specificity:Expression is restricted to melanoma and melanocyte cell lines and retina.,

细胞定位 : Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.

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