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Manic Fringe Polyclonal Antibody

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说明书下载
货号: PD4975
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Manic Fringe
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 38kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Manic Fringe Polyclonal Antibody detects endogenous levels of Manic Fringe protein.
基因名称 : MFNG
蛋白名称 : Beta-1,3-N-acetylglucosaminyltransferase manic fringe
别名 : MFNG;Beta-1;3-N-acetylglucosaminyltransferase manic fringe;O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009],

细胞定位 : Golgi apparatus membrane ; Single-pass type II membrane protein .

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