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LARG Polyclonal Antibody

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说明书下载
货号: PD5065
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: LARG
应用: WB,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 173kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : LARG Polyclonal Antibody detects endogenous levels of LARG protein.
基因名称 : ARHGEF12
蛋白名称 : Rho guanine nucleotide exchange factor 12
别名 : ARHGEF12;KIAA0382;LARG;Rho guanine nucleotide exchange factor 12;Leukemia-associated RhoGEF

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

细胞定位 : Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .

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