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IL-17Rα Polyclonal Antibody

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说明书下载
货号: PD5229
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: IL-17Rα
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 90kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.
基因名称 : IL17RA
蛋白名称 : Interleukin-17 receptor A
别名 : IL17RA;IL17R;Interleukin-17 receptor A;IL-17 receptor A;IL-17RA;CDw217;CD antigen CD217

数据库链接:

Organism

基因 ID

SwissProt

背景:

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],

细胞定位 : [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .

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