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Frizzled-7 Polyclonal Antibody

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说明书下载
货号: PD5673
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Frizzled-7
应用: WB,Flow Cyt,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 64kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;Flow Cyt 1:50-200;IF/ICC1:100-500;ELISA 1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein.
基因名称 : FZD7
蛋白名称 : Frizzled-7
别名 : FZD7;Frizzled-7;Fz-7;hFz7;FzE3

数据库链接:

Organism

基因 ID

SwissProt

背景:

frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2). Localized in recycling endosomes in other conditions. .

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