信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

EDG-1 Polyclonal Antibody

复制产品信息

说明书下载
货号: PD5930
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
undefined
undefined
undefined
+
  • undefined
  • undefined
  • undefined


靶点: EDG-1
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 43kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : EDG-1 Polyclonal Antibody detects endogenous levels of EDG-1 protein.
基因名称 : S1PR1
蛋白名称 : Sphingosine 1-phosphate receptor 1
别名 : S1PR1;CHEDG1;EDG1;Sphingosine 1-phosphate receptor 1;S1P receptor 1;S1P1;Endothelial differentiation G-protein coupled receptor 1;Sphingosine 1-phosphate receptor Edg-1;S1P receptor Edg-1;CD antigen CD363

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

细胞定位 : Cell membrane ; Multi-pass membrane protein. Endosome. Membrane raft. Recruited to caveolin-enriched plasma membrane microdomains in response to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine. Ligand binding leads to receptor internalization.

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交