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EAAT3 Polyclonal Antibody

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说明书下载
货号: PD5940
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: EAAT3
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 57kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : EAAT3 Polyclonal Antibody detects endogenous levels of EAAT3 protein.
基因名称 : SLC1A1
蛋白名称 : Excitatory amino acid transporter 3
别名 : SLC1A1;EAAC1;EAAT3;Excitatory amino acid transporter 3;Excitatory amino-acid carrier 1;Neuronal and epithelial glutamate transporter;Sodium-dependent glutamate/aspartate transporter 3;Solute carrier family 1 member 1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010],

细胞定位 : Cell membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome . Early endosome membrane . Late endosome membrane . Recycling endosome membrane .

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