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DR4 Polyclonal Antibody

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说明书下载
货号: PD5977
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: DR4
应用: WB,IF,ELISA
反应性 : Human,Monkey
宿主物种 : Rabbit
MW(Observed): 50kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : DR4 Polyclonal Antibody detects endogenous levels of DR4 protein.
基因名称 : TNFRSF10A
蛋白名称 : Tumor necrosis factor receptor superfamily member 10A
别名 : TNFRSF10A;APO2;DR4;TRAILR1;Tumor necrosis factor receptor superfamily member 10A;Death receptor 4;TNF-related apoptosis-inducing ligand receptor 1;TRAIL receptor 1;TRAIL-R1;CD antigen CD261

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane ; Single-pass type I membrane protein . Membrane raft . Cytoplasm, cytosol . Palmitoylation is required for association with membranes. .

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