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推荐稀释比 ： WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： DD3 Polyclonal Antibody detects endogenous levels of DD3 protein.
基因名称 ： AKR1C3
蛋白名称 ： Aldo-keto reductase family 1 member C3
别名 ： AKR1C3;DDH1;HSD17B5;KIAA0119;PGFS;Aldo-keto reductase family 1 member C3;17-beta-hydroxysteroid dehydrogenase type 5;17-beta-HSD 5;3-alpha-HSD type II;brain;3-alpha-hydroxysteroid dehydrogenase type 2;3-alpha-HSD type 2;Chlordec
背景：
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
细胞定位 ： Cytoplasm .
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