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货号: PD6153
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: CYP2C8/9/18/19
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 60kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : CYP2C8/9/18/19 Polyclonal Antibody detects endogenous levels of CYP2C8/9/18/19 protein.
基因名称 : CYP2C8/9/18/19
蛋白名称 : Cytochrome P450 2C8/9/18/19
别名 : CYP2C8;Cytochrome P450 2C8;CYPIIC8;Cytochrome P450 IIC2;Cytochrome P450 MP-12;Cytochrome P450 MP-20;Cytochrome P450 form 1;S-mephenytoin 4-hydroxylase;CYP2C9;CYP2C10;Cytochrome P450 2C9;R;-limonene 6-monooxygenase;S;-limonene
数据库链接:
背景:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],


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