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CYP24A1 Polyclonal Antibody

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说明书下载
货号: PD6168
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CYP24A1
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 38kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CYP24A1 Polyclonal Antibody detects endogenous levels of CYP24A1 protein.
基因名称 : CYP24A1
蛋白名称 : 1,25-dihydroxyvitamin D(3) 24-hydroxylase mitochondrial
别名 : CYP24A1;CYP24;1;25-dihydroxyvitamin D;3;24-hydroxylase, mitochondrial;24-OHase;Vitamin D;3;24-hydroxylase;Cytochrome P450 24A1;Cytochrome P450-CC24

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

cytochrome P450 family 24 subfamily A member 1(CYP24A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Mitochondrion .

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