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货号: PD6175
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: CYP1A1/2
应用： WB,IHC,IF,ELISA
反应性 ： Human,Mouse,Rat,Monkey
宿主物种 ： Rabbit
MW(Observed)： 58kD
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： CYP1A1/2 Polyclonal Antibody detects endogenous levels of CYP1A1/2 protein.
基因名称 ： CYP1A1/CYP1A2
蛋白名称 ： Cytochrome P450 1A1/2
别名 ： CYP1A1;Cytochrome P450 1A1;CYPIA1;Cytochrome P450 form 6;Cytochrome P450-C;Cytochrome P450-P1;CYP1A2;Cytochrome P450 1A2;CYPIA2;Cytochrome P;3;450;Cytochrome P450 4;Cytochrome P450-P3
数据库链接：
Organism
基因 ID
SwissProt
Mouse
背景：
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016],
细胞定位 ： Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion inner membrane ; Peripheral membrane protein . Microsome membrane ; Peripheral membrane protein . Cytoplasm .
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