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CYB5R3 Polyclonal Antibody

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说明书下载
货号: PD6196
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: CYB5R3
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 34kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CYB5R3 Polyclonal Antibody detects endogenous levels of CYB5R3 protein.
基因名称 : CYB5R3
蛋白名称 : NADH-cytochrome b5 reductase 3
别名 : CYB5R3;DIA1;NADH-cytochrome b5 reductase 3;B5R;Cytochrome b5 reductase;Diaphorase-1

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010],

细胞定位 : [Isoform 1]: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side.; [Isoform 2]: Cytoplasm. Produces the soluble form found in erythrocytes.

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