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CD30-L Polyclonal Antibody

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说明书下载
货号: PD6546
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CD30-L
应用: WB,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 30kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CD30-L Polyclonal Antibody detects endogenous levels of CD30-L protein.
基因名称 : TNFSF8
蛋白名称 : Tumor necrosis factor ligand superfamily member 8
别名 : TNFSF8;CD30L;CD30LG;Tumor necrosis factor ligand superfamily member 8;CD30 ligand;CD30-L;CD antigen CD153

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

细胞定位 : Membrane; Single-pass type II membrane protein.

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