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AKAP 13 Polyclonal Antibody

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说明书下载
货号: PD7048
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: AKAP 13
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 307kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : AKAP 13 Polyclonal Antibody detects endogenous levels of AKAP 13 protein.
基因名称 : AKAP13
蛋白名称 : A-kinase anchor protein 13
别名 : AKAP13;BRX;HT31;LBC;A-kinase anchor protein 13;AKAP-13;AKAP-Lbc;Breast cancer nuclear receptor-binding auxiliary protein;Guanine nucleotide exchange factor Lbc;Human thyroid-anchoring protein 31;Lymphoid blast crisis oncogene;LBC

数据库链接:

Organism

基因 ID

SwissProt

背景:

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addi

细胞定位 : Cytoplasm, cytosol . Cytoplasm . Cytoplasm, cell cortex . Nucleus . Membrane ; Peripheral membrane protein . Colocalizes with the actin cytoskeleton at the cell cortex. .

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