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ADAR1 Polyclonal Antibody

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说明书下载
货号: PD7088
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ADAR1
应用: IHC,IF,WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 135kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : ADAR1 Polyclonal Antibody detects endogenous levels of ADAR1 protein.
基因名称 : ADAR
蛋白名称 : Double-stranded RNA-specific adenosine deaminase
别名 : ADAR;ADAR1;DSRAD;G1P1;IFI4;Double-stranded RNA-specific adenosine deaminase;DRADA;136 kDa double-stranded RNA-binding protein;p136;Interferon-inducible protein 4;IFI-4;K88DSRBP

数据库链接:

Organism

基因 ID

SwissProt

背景:

adenosine deaminase, RNA specific(ADAR) Homo sapiens This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010],

细胞定位 : [Isoform 1]: Cytoplasm . Nucleus . Shuttles between the cytoplasm and nucleus (PubMed:7565688, PubMed:24753571). Nuclear import is mediated by TNPO1 (PubMed:24753571). .; [Isoform 5]: Cytoplasm . Nucleus . Nucleus, nucleolus . Predominantly nuclear but can shuttle between nucleus and cytoplasm. TNPO1 can mediate its nuclear import whereas XPO5 can mediate its nuclear export. .

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