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货号: PF0248
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: PDE3A
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 126kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of PDE3A (Phospho-Ser312) at Human, Mouse,Rat
基因名称 : PDE3A
蛋白名称 : cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
别名 : cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A;Cyclic GMP-inhibited phosphodiesterase A;CGI-PDE A;cGI-PDE;cGMP-inhibited cAMP phosphodiesterase;
背景:
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],


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