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ROR1 (Phospho Tyr786) rabbit pAb

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说明书下载
货号: PF0288
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ROR1
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 105kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of ROR1 (Phospho-Tyr786) at Human, Mouse,Rat
基因名称 : ROR1 NTRKR1
蛋白名称 : ROR1 (Phospho-Tyr786)
别名 : Tyrosine-protein kinase transmembrane receptor ROR1;Neurotrophic tyrosine kinase, receptor-related 1;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012],

细胞定位 : Membrane ; Single-pass type I membrane protein. Cell projection, axon .

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