组成
:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
:
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
:
-15°C to -25°C/1 year(Do not lower than -25°C
浓度
:
1 mg/ml
克隆性
:
Polyclonal
抗原&靶点信息
特异性
:
This antibody detects endogenous levels of Human,Mouse,Rat Smad2 (Phospho Ser245)
基因名称
:
SMAD2 MADH2 MADR2
蛋白名称
:
Smad2 (Phospho Ser245)
别名
:
Mothers against decapentaplegic homolog 2;MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2;
细胞定位
:
Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1 (PubMed:16751101, PubMed:19289081). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .