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IRAK-1 (phospho Thr387) Polyclonal Antibody

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说明书下载
货号: PF0757
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: IRAK-1
应用: WB,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 77kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-IRAK-1 (T387) Polyclonal Antibody detects endogenous levels of IRAK-1 protein only when phosphorylated at T387.
基因名称 : IRAK1
蛋白名称 : Interleukin-1 receptor-associated kinase 1
别名 : IRAK1;IRAK;Interleukin-1 receptor-associated kinase 1;IRAK-1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity). .

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