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MOR-1 (phospho Ser375) Polyclonal Antibody

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说明书下载
货号: PF0965
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MOR-1
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 45kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-MOR-1 (S375) Polyclonal Antibody detects endogenous levels of MOR-1 protein only when phosphorylated at S375.
基因名称 : OPRM1
蛋白名称 : Mu-type opioid receptor
别名 : OPRM1;MOR1;Mu-type opioid receptor;M-OR-1;MOR-1;Mu opiate receptor;Mu opioid receptor;MOP;hMOP

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013],

细胞定位 : Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Perikaryon . Cell projection, dendrite . Endosome . Is rapidly internalized after agonist binding. .; [Isoform 12]: Cytoplasm .

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