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ENaC β (phospho Thr615) Polyclonal Antibody

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说明书下载
货号: PF0977
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ENaC β
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 68kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-ENaC β (T615) Polyclonal Antibody detects endogenous levels of ENaC β protein only when phosphorylated at T615.
基因名称 : SCNN1B
蛋白名称 : Amiloride-sensitive sodium channel subunit beta
别名 : SCNN1B;Amiloride-sensitive sodium channel subunit beta;Beta-NaCH;Epithelial Na;+;channel subunit beta;Beta-ENaC;ENaCB;Nonvoltage-gated sodium channel 1 subunit beta;SCNEB

数据库链接:

Organism

基因 ID

SwissProt

背景:

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009],

细胞定位 : Apical cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Apical membrane of epithelial cells. .

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