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Histone H1 (phospho Thr17) Polyclonal Antibody

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说明书下载
货号: PF0993
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: Histone H1
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Monkey
宿主物种 : Rabbit
MW(Observed): 31kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-Histone H1 (T17) Polyclonal Antibody detects endogenous levels of Histone H1 protein only when phosphorylated at T17.
基因名称 : HIST1H1B
蛋白名称 : Histone H1.5
别名 : HIST1H1B;H1F5;Histone H1.5;Histone H1a;Histone H1b;Histone H1s-3;HIST1H1D;H1F3;Histone H1.3;Histone H1c;Histone H1s-2;HIST1H1E;H1F4;Histone H1.4;Histone H1b;Histone H1s-4

数据库链接:

Organism

基因 ID

SwissProt

背景:

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],

细胞定位 : Nucleus. Chromosome. According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin.

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