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货号: PF1118
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: SPAK
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 60kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : Phospho-SPAK (S311) Polyclonal Antibody detects endogenous levels of SPAK protein only when phosphorylated at S311.
基因名称 : STK39
蛋白名称 : STE20/SPS1-related proline-alanine-rich protein kinase
别名 : STK39;SPAK;STE20/SPS1-related proline-alanine-rich protein kinase;Ste-20-related kinase;DCHT;Serine/threonine-protein kinase 39
背景:
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008],


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