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HSL (phospho Ser552) Polyclonal Antibody

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说明书下载
货号: PF1281
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: HSL
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 117kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-HSL (S552) Polyclonal Antibody detects endogenous levels of HSL protein only when phosphorylated at S552.
基因名称 : LIPE
蛋白名称 : Hormone-sensitive lipase
别名 : LIPE;Hormone-sensitive lipase;HSL

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane . Membrane, caveola . Cytoplasm, cytosol . Lipid droplet . Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation (PubMed:17026959). Phosphorylation by AMPK reduces its translocation towards the lipid droplets (By similarity). .

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