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Neuro D (phospho Ser274) Polyclonal Antibody

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说明书下载
货号: PF1443
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Neuro D
应用: WB,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 36kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-Neuro D (S274) Polyclonal Antibody detects endogenous levels of Neuro D protein only when phosphorylated at S274.
基因名称 : NEUROD1
蛋白名称 : Neurogenic differentiation factor 1
别名 : NEUROD1;BHLHA3;NEUROD;Neurogenic differentiation factor 1;NeuroD;NeuroD1;Class A basic helix-loop-helix protein 3;bHLHa3

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Nucleus . In pancreatic islet cells, shuttles to the nucleus in response to glucose stimulation (By similarity). Colocalizes with NR0B2 in the nucleus. .

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