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ATRIP (phospho Ser68) Polyclonal Antibody

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说明书下载
货号: PF1580
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ATRIP
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 80kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-ATRIP (S68) Polyclonal Antibody detects endogenous levels of ATRIP protein only when phosphorylated at S68.
基因名称 : ATRIP
蛋白名称 : ATR-interacting protein
别名 : ATRIP;AGS1;ATR-interacting protein;ATM and Rad3-related-interacting protein

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],

细胞定位 : Nucleus . Redistributes to discrete nuclear foci upon DNA damage.

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