信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

Csk (phospho Ser364) Polyclonal Antibody

复制产品信息

说明书下载
货号: PF1620
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
undefined
+
  • undefined


靶点: Csk
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 55kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-Csk (S364) Polyclonal Antibody detects endogenous levels of Csk protein only when phosphorylated at S364.
基因名称 : CSK
蛋白名称 : Tyrosine-protein kinase CSK
别名 : CSK;Tyrosine-protein kinase CSK;C-Src kinase;Protein-tyrosine kinase CYL

数据库链接:

Organism

基因 ID

SwissProt

背景:

catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Mainly cytoplasmic, also present in lipid rafts.,subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.,tissue specificity:Expressed in lung and macrophages.,

细胞定位 : Cytoplasm . Cell membrane . Mainly cytoplasmic, also present in lipid rafts. .

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交