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AMPKα1 (Phospho Ser485) rabbit pAb

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说明书下载
货号: PF0663
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: AMPKα1
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 65kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human Mouse Rat AMPKα1 (phospho-Ser485)
基因名称 : PRKAA1 AMPK1
蛋白名称 : AMPKα1 (Ser485)
别名 : 5'-AMP-activated protein kinase catalytic subunit alpha-1;AMPK subunit alpha-1;Acetyl-CoA carboxylase kinase;ACACA kinase;Hydroxymethylglutaryl-CoA reductase kinase;HMGCR kinase;Tau-protein kinase PRKAA1;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .

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