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53BP2/ASPP2 Rabbit mAb

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说明书下载
货号: PL0770
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ASPP2
应用: WB,IHC,IF,ICC
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 124kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:1000-5000;IHC 1:100-300;ICC/IF 1:100-300
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0791R

抗原&靶点信息

特异性 : Endogenous
基因名称 : TP53BP2;ASPP2;BBP
蛋白名称 : Apoptosis-stimulating of p53 protein 2
别名 : TP53BP2;ASPP2;BBP;Apoptosis-stimulating of p53 protein 2 ;Bcl2-binding protein;Bbp;Renal carcinoma antigen NY-REN-51;Tumor suppressor p53-binding protein 2;53BP2;p53-binding protein 2;p53BP2;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm, perinuclear region. Nucleus. Note=Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42.

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