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Neurofilament (ABT456) mouse mAb

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说明书下载
货号: PH0141
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: NF-L
应用: IHC,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Mouse
MW(CalcμLated) : 68kD
MW(Observed): 68kD
同种型-Isotype : IgG1,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-400;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT456

抗原&靶点信息

特异性 : The antibody can specifically recognize human Neurofilament protein, especilaly NF-L protein.
基因名称 : NEFL NF68 NFL
蛋白名称 : Neurofilament light polypeptide;NF-L;Neurofilament triplet L protein;68 kDa neurofilament protein;
别名 : Neurofilament light polypeptide;NF-L;68 kDa neurofilament protein;Neurofilament triplet L protein;

数据库链接:

Organism

基因 ID

SwissProt

背景:

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008],

细胞定位 : Cytoplasmic

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