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IRF-4/MUM1 (ABT080) mouse mAb

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说明书下载
货号: PH0145
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MUM1
应用: IHC,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(CalcμLated) : 52kD
MW(Observed): 52kD
同种型-Isotype : IgG1,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-400;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT080

抗原&靶点信息

特异性 : The antibody can specifically recognize human MUM1 protein.
基因名称 : IRF4 MUM1
蛋白名称 : Interferon regulatory factor 4
别名 : Interferon regulatory factor 4;IRF-4;Lymphocyte-specific interferon regulatory factor;LSIRF;Multiple myeloma oncogene 1;NF-EM5;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010],

细胞定位 : Nuclear

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