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详细信息
推荐稀释比 : IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0972R
抗原&靶点信息
特异性 : Endogenous
基因名称 : EIF2AK4
蛋白名称 : Eukaryotic translation initiation factor 2-alpha kinase 4
别名 : EIF2AK4;GCN2;KIAA1338;Eukaryotic translation initiation factor 2-alpha kinase 4;GCN2-like protein
背景:
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014],


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