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IGF2-BP2 (PT1532R) PT™ Rabbit mAb

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说明书下载
货号: PL0243
货期: 现货
价格: 100μL/1800
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靶点: IGF2-BP2
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 66kD
MW(Observed): 66kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Endogenous
基因名称 : IGF2BP2
蛋白名称 : Insulin-like growth factor 2 mRNA-binding protein 2
别名 : IGF2BP2;IMP2;VICKZ2;Insulin-like growth factor 2 mRNA-binding protein 2;IGF2 mRNA-binding protein 2;IMP-2;Hepatocellular carcinoma autoantigen p62;IGF-II mRNA-binding protein 2;VICKZ family member 2

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016],

细胞定位 : Nucleus. Cytoplasm. Cytoplasm, P-body . Cytoplasm, Stress granule . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa. In response to cellular stress, such as oxidative stress, recruited to stress granules.

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