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Amyloid-β (1-42) Rabbit mAb

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说明书下载
货号: PL0284
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Amyloid-β
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 87kD
MW(Observed): 100kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Endogenous
基因名称 : APP
蛋白名称 : Amyloid beta A4 protein, Amyloid-β, Aβ
别名 : APP;A4;AD1;Amyloid beta A4 protein;ABPP;APPI;APP;Alzheimer disease amyloid protein;Cerebral vascular amyloid peptide;CVAP;PreA4;Protease nexin-II;PN-II

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind toThe acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others formThe protein basis ofThe amyloid plaques found inThe brains of patients with Alzheimer disease. In addition, two ofThe peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014],

细胞定位 : Membrane

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