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Smo Rabbit mAb

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说明书下载
货号: PL0390
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Smo
应用: WB,IF,IP,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 86kD
MW(Observed): 100kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT1379R

抗原&靶点信息

特异性 : Endogenous
基因名称 : SMO
蛋白名称 : Smoothened homolog
别名 : SMO;SMOH;Smoothened homolog;SMO;Protein Gx

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010],

细胞定位 : Disease:Defects in SMO are involved in basal cell carcinoma (BCC).,Function:G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO).,similarity:Belongs to the G-protein coupled receptor Fz/Smo family.,similarity:Contains 1 FZ (frizzled) domain.,

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