储存
:
-15°C to -25°C/1 year(Do not lower than -25°C
克隆性
:
Monoclonal
克隆号
:
PT1240R
抗原&靶点信息
特异性
:
Endogenous
基因名称
:
SCARB1 CD36L1 CLA1
蛋白名称
:
Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)
细胞定位
:
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells . Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux . Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity . ; (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry . Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate . ; (Microbial infection) Mediates uptake of M.fortuitum, E.coli and S.aureus. ; (Microbial infection) Facilitates the entry of human coronavirus SARS-CoV-2 by acting as an entry cofactor through HDL binding.