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货号: PL0790
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: IκB α
应用： WB,IF,IP,ELISA
反应性 ： Human,Mouse,Rat
宿主物种 ： Rabbit
MW(CalcμLated) ： 36kD
MW(Observed)： 40kD
同种型-Isotype ： IgG,Kappa
偶联-Conjugate ： Phospho
隐藏域元素占位
详细信息
修饰-Modification ： Ser32
推荐稀释比 ： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 ： Protein A
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 ： PT0899R
抗原&靶点信息
特异性 ： IκB-α (Phospho Ser32) antibody detects endogenous levels of IκB-α only when phosphorylated at Ser32.and dually phosphorylated at two sites.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):HDsGL
基因名称 ： NFKBIA IKBA MAD3 NFKBI
蛋白名称 ： NF-kappa-B inhibitor alpha
别名 ： NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;
背景：
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],
细胞定位 ： Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. .
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