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货号: PL0825
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: MRP1
应用: WB,IHC,IF,IP,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 172kD
MW(Observed): 170-220kD
同种型-Isotype : IgG,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal
抗原&靶点信息
特异性 : Endogenous
基因名称 : ABCC1 MRP MRP1
蛋白名称 : Multidrug resistance-associated protein 1 (ATP-binding cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter)
背景:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012],


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