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Sortilin Rabbit mAb

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说明书下载
货号: PL0832
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Sortilin
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 92kD
MW(Observed): 100kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : PT0943R

抗原&靶点信息

特异性 : Endogenous
基因名称 : SORT1
蛋白名称 : Sortilin
别名 : SORT;Sortilin;100 kDa NT receptor;Glycoprotein 95;Gp95;Neurotensin receptor 3;NT3;NTR3;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

细胞定位 : Golgi apparatus, Golgi stack membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Nucleus membrane ; Single-pass type I membrane protein . Cell membrane; Single-pass type I membrane protein; Extracellular side. Lysosome membrane ; Single-pass type I membrane protein . Localized to membranes of the endoplasmic reticulum, endosomes, Golgi stack, lysosomes and nucleus. A small fraction of the protein is also localized to the plasma membrane. May also be found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes. Localization to the plasma membrane in adipocytes may be enhanced by insulin.

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