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Erk 1/2 (Phospho Thr202/Tyr204) Rabbit mAb

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说明书下载
货号: PL1096
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ERK 1/2 Phospho Thr202/Tyr204
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 44kD,42kD
MW(Observed): 44kD,42kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Phospho

隐藏域元素占位

详细信息

修饰-Modification : Thr202/Tyr204
推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0643R

抗原&靶点信息

特异性 : This antibody detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when dually phosphorylated at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2), and Erk2 singly phosphorylated at Thr185, and Erk1 singly phosphorylated at Thr202
基因名称 : MAPK1/MAPK3
蛋白名称 : Mitogen-activated protein kinase 3
别名 : MAPK3;ERK1;PRKM3;Mitogen-activated protein kinase 3;MAP kinase 3;MAPK 3;ERT2;Extracellular signal-regulated kinase 1;ERK-1;Insulin-stimulated MAP2 kinase;MAP kinase isoform p44;p44-MAPK;Microtubule-associated protein 2 kinase;p

数据库链接:

背景:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm, Nucleus

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