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Estrogen Receptor α Rabbit mAb

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说明书下载
货号: PL1107
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ESR1
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 66kD
MW(Observed): 66kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0632R

抗原&靶点信息

特异性 : Endogenous
基因名称 : Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
蛋白名称 : Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
别名 : ESR1 ESR NR3A1

数据库链接:

Organism

基因 ID

SwissProt

背景:

estrogen receptor 1(ESR1) Homo sapiens This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014],

细胞定位 : Nucleus

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