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ERK5 Rabbit mAb

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说明书下载
货号: PL1188
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ERK 5
应用: WB,IF,IP,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 88kD
MW(Observed): 115kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0140R

抗原&靶点信息

特异性 : Endogenous
基因名称 : MAPK7,ERK5
蛋白名称 : Mitogen-activated protein kinase 7
别名 : MAPK7;BMK1;ERK5;PRKM7;Mitogen-activated protein kinase 7;MAP kinase 7;MAPK 7;Big MAP kinase 1;BMK-1;Extracellular signal-regulated kinase 5;ERK-5

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm, Nucleus

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