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Oct-4 Rabbit mAb

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说明书下载
货号: PL1275
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Oct 3/4
应用: WB,IHC,IF,IP,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 39kD
MW(Observed): 45kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0430R

抗原&靶点信息

特异性 : Endogenous
基因名称 : POU5F1
蛋白名称 : POU domain class 5 transcription factor 1
别名 : POU5F1;OCT3;OCT4;OTF3;POU domain; class 5, transcription factor 1;Octamer-binding protein 3;Oct-3;Octamer-binding protein 4;Oct-4;Octamer-binding transcription factor 3;OTF-3

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation withThe Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One ofThe AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013],

细胞定位 : Nucleus

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