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Glutamine Synthetase Rabbit mAb

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说明书下载
货号: PL1514
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Glutamine Synthetase
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Rabbit
MW(CalcμLated) : 42kD
MW(Observed): 42kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0057R

抗原&靶点信息

特异性 : Endogenous
基因名称 : >>Arginine biosynthesis;>>Alanine, aspartate and glutamate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Nitrogen metabolism;>>Metabolic pathways;>>Biosynthesis of amino acids;>>Necroptosis;>>Glutamatergic synapse;>>GABAergic synapse
蛋白名称 : Glutamine synthetase
别名 : GLUL;GLNS;Glutamine synthetase;GS;Glutamate decarboxylase;Glutamate--ammonia ligase

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

细胞定位 : Cytoplasm, Membrane

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