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详细信息
推荐稀释比 : IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0057R
抗原&靶点信息
特异性 : Endogenous
基因名称 : >>Arginine biosynthesis;>>Alanine, aspartate and glutamate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Nitrogen metabolism;>>Metabolic pathways;>>Biosynthesis of amino acids;>>Necroptosis;>>Glutamatergic synapse;>>GABAergic synapse
蛋白名称 : Glutamine synthetase
别名 : GLUL;GLNS;Glutamine synthetase;GS;Glutamate decarboxylase;Glutamate--ammonia ligase
背景:
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],


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