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详细信息
推荐稀释比 ： IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
组成 ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 ： The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 ： Monoclonal
克隆号 ： PT2024
抗原&靶点信息
特异性 ： The antibody can specifically recognize human Mast cell tryptase protein.
基因名称 ： TPSAB1 TPS1 TPS2 TPSB1
蛋白名称 ： Tryptase alpha/beta-1 (Tryptase-1) (Tryptase I) (Tryptase alpha-1)
背景：
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene
细胞定位 ： Cytoplasmic
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