信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

Claudin 18.1 (PT0108) mouse mAb

复制产品信息

说明书下载
货号: PH0262
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
undefined
+
  • undefined


靶点: Claudin 18
应用: IHC,IF,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Mouse
MW(CalcμLated) : 28kD
同种型-Isotype : IgG1,Lambda

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0108

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Claudin 18.1 protein.
基因名称 : CLDN18 UNQ778/PRO1572
蛋白名称 : Claudin 18
别名 : Claudin 18 antibody;Claudin-18 antibody;CLD18_HUMAN antibody;CLDN18 antibody;SFTA5 antibody;SFTPJ antibody;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]

细胞定位 : Membranous

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交