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货号: PG7890
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: LRBA
应用: IHC,IF
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 314kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:50-300;IF 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : LRBA Polyclonal Antibody detects endogenous levels of protein.
基因名称 : LRBA BGL CDC4L LBA
蛋白名称 : Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) (CDC4-like protein)
背景:
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],


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