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LRBA Polyclonal Antibody

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说明书下载
货号: PG7890
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: LRBA
应用: IHC,IF
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 314kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:50-300;IF 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : LRBA Polyclonal Antibody detects endogenous levels of protein.
基因名称 : LRBA BGL CDC4L LBA
蛋白名称 : Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) (CDC4-like protein)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

细胞定位 : Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass membrane protein . Lysosome membrane ; Single-pass membrane protein .

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