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PTPα Polyclonal Antibody

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说明书下载
货号: PD3907
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: PTPα
应用: WB,ELISA,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 90kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : PTPα Polyclonal Antibody detects endogenous levels of PTPα protein.
基因名称 : PTPRA
蛋白名称 : Receptor-type tyrosine-protein phosphatase alpha
别名 : PTPRA;PTPA;PTPRL2;Receptor-type tyrosine-protein phosphatase alpha;Protein-tyrosine phosphatase alpha;R-PTP-alpha

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane ; Single-pass type I membrane protein . Cell junction, focal adhesion . Localizes to focal adhesion sites following integrin engagement. .

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