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货号: PD3907
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: PTPα
应用: WB,ELISA,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 90kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : PTPα Polyclonal Antibody detects endogenous levels of PTPα protein.
基因名称 : PTPRA
蛋白名称 : Receptor-type tyrosine-protein phosphatase alpha
别名 : PTPRA;PTPA;PTPRL2;Receptor-type tyrosine-protein phosphatase alpha;Protein-tyrosine phosphatase alpha;R-PTP-alpha
背景:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008],


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