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详细信息
推荐稀释比 ： IHC 1:1000-1:4000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 ： Protein A
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 ： Monoclonal
克隆号 ： PT0402R
抗原&靶点信息
特异性 ： Endogenous
基因名称 ： TGFB1 TGFB3
蛋白名称 ： Transforming growth factor beta-1 proprotein;Latency-associated peptide(LAP);Transforming growth factor beta-1(TGF-beta-1);Transforming growth factor beta-3 proprotein;Transforming growth factor beta-3 (TGF-beta-3);
别名 ： Transforming growth factor beta-1 proprotein;Latency-associated peptide;LAP;Transforming growth factor beta-1;TGF-beta-1;Transforming growth factor beta-3 proprotein;Transforming growth factor beta-3;TGF-beta-3;
数据库链接：
Organism
基因 ID
SwissProt
背景：
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic
细胞定位 ： Secreted
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